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Ibuprofen Orange Pill G2: A Guide to Uses, Safety, and Side Effects

Ibuprofen Orange Pill G2: A Guide to Uses, Safety, and Side Effects

Table of Contents

The orange pill marked “G2” is a widely recognized over-the-counter medication containing 200 mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID). As a cornerstone in pain management, this medication is commonly used to alleviate mild to moderate pain, reduce inflammation, and lower fever. Its accessibility and effectiveness make it a popular choice for addressing conditions such as headaches, menstrual cramps, arthritis, muscle aches, back pain, toothaches, and the symptoms of colds and flu.


This guide aims to provide comprehensive and accurate information about the G2 pill, including its uses, safety precautions, and potential side effects. Whether you are considering using this medication for the first time or seeking to deepen your understanding of its proper usage, this article will equip you with actionable insights to ensure safe and effective relief.

Dosage and Administration

The recommended dosage for adults and children over 12 years is one or two tablets (200–400 mg) every 4 to 6 hours as needed. It is crucial not to exceed six tablets (1200 mg) within a 24-hour period unless directed by a healthcare provider. For optimal results and safety:

  • Take the pill with food or milk to minimize stomach irritation.
  • Maintain at least a four-hour interval between doses.
  • Follow all instructions on the packaging or those provided by a healthcare professional.

Safety Precautions

While ibuprofen is generally safe when used as directed, certain precautions should be observed:

  1. Avoid Long-Term Use: Prolonged use or high doses can increase the risk of gastrointestinal bleeding, kidney damage, or cardiovascular events.
  2. Medical Conditions: Consult a doctor before use if you have pre-existing conditions such as heart disease, high blood pressure, kidney issues, or a history of stomach ulcers.
  3. Pregnancy and Breastfeeding: Pregnant women should avoid ibuprofen due to potential risks to the fetus. Breastfeeding mothers should consult their doctor before use.
  4. Drug Interactions: Inform your healthcare provider about any other medications you are taking to avoid adverse interactions.

Potential Side Effects

Like all medications, ibuprofen may cause side effects. Common side effects include:

  • Nausea
  • Heartburn
  • Dizziness
  • Mild stomach upset

Serious but rare side effects include severe allergic reactions (rash, swelling of the face or throat), gastrointestinal bleeding (black stools or vomiting blood), and kidney problems (reduced urine output). If you experience any severe symptoms, seek medical attention immediately.

What is the Orange Pill G2?

The orange pill with the imprint “G2” is a common sight in many medicine cabinets. This small, round tablet is easily recognizable by its bright orange color and the distinct “G2” marking on its surface.


Manufactured by Granules Pharmaceuticals, this pill contains 200 mg of ibuprofen, a widely used non-steroidal anti-inflammatory drug (NSAID). Ibuprofen is known for its effectiveness in reducing pain, fever, and inflammation, making it a go-to choice for many people seeking relief from various ailments.


One of the key advantages of the G2 pill is its accessibility. As an over-the-counter medication, it can be purchased without a prescription, providing convenient relief for mild to moderate pain. Whether you’re dealing with a headache, menstrual cramps, toothache, or minor muscle aches, this orange pill offers a readily available solution.


Granules Pharmaceuticals, the company behind the G2 pill, is recognized as one of the largest manufacturers of first-line defense products, including ibuprofen. Their commitment to producing safe, effective, and high-quality drugs has made them a trusted name in the pharmaceutical industry.


The G2 pill’s design as a round, orange tablet isn’t just for aesthetic purposes. This distinctive appearance helps users easily identify the medication, reducing the risk of confusion with other pills. The “G2” imprint serves as a unique identifier, allowing for quick verification using pill identification tools if needed.

As with any medication, it’s important to use the G2 pill responsibly and follow the recommended dosage guidelines. While it offers effective pain relief for many common ailments, users should be aware of potential side effects and consult with a healthcare professional if they have any concerns or pre-existing medical conditions.


In conclusion, the orange G2 pill represents a widely accessible and reliable option for those seeking over-the-counter pain relief. Its recognizable appearance, coupled with the reputation of its manufacturer, Granules Pharmaceuticals, has made it a staple in pain management for many individuals dealing with everyday aches and pains.


The orange pill marked G2 is a common over-the-counter medication containing 200mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) widely used for its pain-relieving, anti-inflammatory, and fever-reducing properties.

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Ibuprofen Orange Pill G2: A Guide to Uses, Safety, and Side Effects-ibuprofeno2.jpg

Common Uses of the Orange Pill G2

Pain Relief: The G2 pill is highly effective in alleviating various types of pain. It’s particularly useful for treating headaches, providing quick relief from the throbbing discomfort that can disrupt daily activities. For those suffering from muscle aches, whether due to overexertion or minor injuries, this medication can significantly reduce pain and improve mobility. Arthritis patients often find relief from joint pain and stiffness with regular use of ibuprofen. The G2 pill is also a go-to solution for toothaches, offering temporary relief until proper dental care can be obtained. Many women rely on ibuprofen to manage menstrual cramps, as it effectively reduces the intensity of pain associated with monthly cycles.


Inflammation Reduction: One of the key benefits of the G2 pill is its ability to reduce inflammation throughout the body. This makes it particularly useful for conditions like tendonitis or bursitis, where swelling can cause significant discomfort and limit movement. By inhibiting the production of prostaglandins through the cyclooxygenase pathway, ibuprofen helps to decrease inflammation, leading to reduced pain and improved function in affected areas. This anti-inflammatory action is what makes the G2 pill so versatile in treating a wide range of conditions involving swelling and tissue irritation.


Fever Reduction: When it comes to managing fever associated with colds and flu, the G2 pill proves to be an invaluable ally. Ibuprofen works by affecting the body’s temperature-regulating center in the brain, helping to bring down elevated body temperatures. This not only provides comfort to those suffering from fever but also helps prevent potential complications associated with prolonged high temperatures. The fever-reducing properties of the G2 pill, combined with its pain-relieving effects, make it a comprehensive solution for addressing multiple symptoms of common illnesses like colds and flu.


While the G2 pill offers numerous benefits, it’s crucial to use it responsibly and as directed. Always follow the recommended dosage and consult with a healthcare professional if symptoms persist or worsen. Remember, while not addictive, long-term or excessive use of NSAIDs like ibuprofen can lead to side effects, particularly in individuals with certain health conditions or those taking other medications. The G2 pill, when used appropriately, remains a valuable tool in managing pain, inflammation, and fever, helping countless individuals find relief and improve their quality of life.

Dosage Guidelines for the Orange Pill G2

When it comes to taking ibuprofen, following the recommended dosage is essential. For adults and children over 12 years old, the typical dosage ranges from 200 to 400 mg every 4 to 6 hours as needed for pain relief. It’s important to note that you should not exceed 1200 mg within a 24-hour period unless specifically directed by a healthcare provider. This limit helps minimize the risk of potential side effects.


For children under 12 years old, dosing can be more complex. Pediatric dosages of ibuprofen are typically based on the child’s age and weight, and it’s crucial to follow a doctor’s or pediatrician’s guidance. Parents should never attempt to determine the appropriate dose for their child without medical advice, as incorrect dosing can lead to serious health issues.


To ensure safe use of ibuprofen, it’s recommended to take it with food or milk. This simple step can help minimize the risk of stomach upset, which is a common side effect of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. Additionally, starting with the lowest effective dose and only increasing if necessary can help reduce the likelihood of adverse effects.


It’s worth noting that while ibuprofen is generally safe when used as directed, it’s not suitable for everyone. People with certain medical conditions or those taking specific medications should consult with a healthcare professional before using ibuprofen. This is especially important for individuals over 60, those with a history of stomach ulcers, or anyone taking blood thinners or steroid medications.


Remember, the key to safely using any medication, including the orange pill G2, is to follow the recommended guidelines and seek medical advice when in doubt. By doing so, you can effectively manage pain and inflammation while minimizing potential risks.

Who Should Avoid This Medication

Certain groups of people should be particularly cautious when considering this medication. Individuals with a history of stomach ulcers should be wary, as the medication can increase the risk of gastrointestinal bleeding. Those with heart disease or kidney issues should also consult their healthcare provider before use, as the medication may exacerbate these conditions.


Older adults, especially those over 65, should be extra vigilant. As we age, our bodies may become more sensitive to medications, increasing the risk of side effects. The medication may also interact with other drugs commonly prescribed to older adults, potentially leading to dangerous complications.


Pregnant women, particularly those in their third trimester, should avoid this medication unless specifically advised by their doctor. The use of certain medications during pregnancy can pose risks to the developing fetus and may lead to complications during childbirth.

Potential Side Effects

Like all medications, this one comes with a range of potential side effects, ranging from common and relatively mild to more serious and potentially life-threatening.


Common side effects include nausea, dizziness, and heartburn. While these symptoms can be uncomfortable, they’re generally not cause for serious concern. However, if they persist or worsen, it’s important to consult with a healthcare provider.


More serious side effects, though less common, require immediate medical attention. Stomach bleeding is a significant risk, especially for those with a history of ulcers or who are taking blood thinners. Kidney damage is another serious concern, particularly for older adults or those with pre-existing kidney issues. Allergic reactions, while rare, can be life-threatening and require immediate emergency care.


It’s crucial to remember that medication safety is a collaborative effort between patients and healthcare providers. Always discuss your full medical history and any concerns with your doctor or pharmacist before starting a new medication. By staying informed and vigilant, we can maximize the benefits of medications while minimizing potential risks.

Drug Interactions with the Orange Pill G2

The orange, oval-shaped pill marked with “G2” is identified as ibuprofen 200 mg, a common over-the-counter nonsteroidal anti-inflammatory drug (NSAID) used for pain relief and reducing inflammation. While ibuprofen is generally safe when used as directed, it’s crucial to be aware of potential drug interactions that could lead to serious health complications.

Medications to Avoid

When taking ibuprofen, it’s important to exercise caution with certain medications. Other NSAIDs, such as aspirin or naproxen, should be avoided as combining them can increase the risk of gastrointestinal ulceration or bleeding. This risk is particularly heightened when ibuprofen is taken alongside corticosteroid medicines like prednisolone.


Blood thinners, including warfarin, clopidogrel (Plavix), and even low-dose aspirin, should not be taken concurrently with ibuprofen. The combination can significantly increase the risk of bleeding. Research has shown that ibuprofen can prolong bleeding time in patients taking warfarin, potentially leading to dangerous complications, especially in elderly patients or those on complex drug regimens.


Diuretics, often prescribed for high blood pressure, pose a particular risk when combined with ibuprofen. This combination, especially when also taken with ACE inhibitors or angiotensin receptor blockers (ARBs), can lead to acute kidney injury. This “triple whammy” effect can cause severe, and in some cases, permanent kidney damage. The risk is highest within the first month of combining these medications.

Alcohol Consumption

Alcohol consumption while taking ibuprofen raises concerns about increased risks of stomach bleeding and liver damage. The combination can irritate the stomach lining and potentially lead to ulcers or gastrointestinal bleeding. Additionally, both alcohol and ibuprofen are metabolized by the liver, potentially increasing the strain on this vital organ.


It’s essential to consult with a healthcare provider or pharmacist before combining ibuprofen with any other medications or alcohol. They can provide personalized advice based on your specific health conditions and medication regimen. Remember, even though ibuprofen is available over-the-counter, it’s a potent medication that requires careful consideration of potential interactions to ensure safe use.


How Long Does the Orange Pill G2 Stay in Your System?
The orange pill G2, commonly known as ibuprofen, is a widely used over-the-counter pain reliever and anti-inflammatory medication. Understanding how long it stays in your system is crucial for proper usage and avoiding potential side effects.
Ibuprofen has a relatively short half-life, typically ranging from 1.8 to 2 hours. This means that after taking a dose, half of the drug is eliminated from your body within this timeframe.


However, it’s important to note that the complete elimination of ibuprofen from your system takes longer. Generally, it takes about 4 to 5 half-lives for a drug to be fully cleared from the body. For ibuprofen, this translates to approximately 10 hours for most of the drug to be eliminated.


Despite its short half-life, the pain-relieving effects of ibuprofen usually last longer than the drug’s presence in your bloodstream. The typical duration of action for ibuprofen is 4 to 6 hours. This is why dosing instructions often recommend taking ibuprofen every 4 to 6 hours for pain relief, as needed.


Several factors can influence how long ibuprofen stays in your system and how quickly it’s metabolized. Age is a significant factor, with older adults potentially experiencing slower metabolism of the drug. Liver function plays a crucial role in ibuprofen metabolism, as the drug is primarily processed by the liver. Individuals with compromised liver function may have a prolonged half-life of ibuprofen, potentially extending to 3.1 to 3.4 hours.


Kidney health is another important consideration. While ibuprofen is primarily metabolized by the liver, its metabolites are excreted through the kidneys. Individuals with kidney issues may experience slower elimination of these metabolites, potentially leading to accumulation in the body.


It’s worth noting that ibuprofen is almost entirely metabolized, with less than 1% of the drug excreted unchanged. The majority of ibuprofen and its metabolites are eliminated through urine, with a small portion excreted in feces.


Understanding the metabolism and duration of action of ibuprofen can help users make informed decisions about dosing and frequency of use. However, it’s always best to follow the recommended dosage instructions and consult with a healthcare professional if you have any concerns about how long ibuprofen may stay in your system, especially if you have pre-existing health conditions or are taking other medications.

Detectability in Drug Tests

When it comes to drug testing, many people have concerns about the substances they consume and how they may affect test results. One common over-the-counter medication, ibuprofen, is often questioned regarding its detectability in drug tests. Generally, ibuprofen is not typically detected in standard drug tests. However, it is important to note that there can be rare instances where ibuprofen may lead to false positives for certain substances.


Ibuprofen, a widely used non-steroidal anti-inflammatory drug (NSAID), is primarily taken for pain relief and inflammation reduction. While it is not a controlled substance and does not usually appear on standard drug screening panels, some studies have indicated that it can interfere with certain immunoassays, potentially leading to false positive results. Specifically, ibuprofen has been associated with false positives for substances like barbiturates, benzodiazepines, and even marijuana in some cases.


Given this possibility, it is crucial for individuals to inform testing authorities about any over-the-counter medications they are using prior to undergoing a drug test. This transparency can help mitigate misunderstandings and ensure that the results are interpreted correctly. In situations where a false positive occurs, individuals may have the option to request more specific testing methods that can accurately differentiate between substances.


In summary, while ibuprofen is not typically detected in standard drug tests, its potential to cause rare false positives warrants caution. By communicating openly about medication use, individuals can navigate the complexities of drug testing more effectively and avoid unnecessary complications.

Proper Storage and Disposal of the Orange Pill G2

When it comes to managing medications, understanding the proper storage and disposal methods is crucial for safety and efficacy. The orange pill G2, identified as Ibuprofen 200 mg, is commonly used as a pain reliever and anti-inflammatory. To ensure that this medication remains effective and to prevent potential hazards, it is essential to follow specific guidelines for both storage and disposal.

Storage Tips

The G2 pill should be stored in a cool, dry place. This means avoiding locations that are prone to humidity or temperature fluctuations, such as bathrooms or kitchens. Instead, opt for a storage area that is consistently cool and away from direct sunlight. Keeping the medication in its original container is also advisable, as this helps protect it from moisture and light exposure. Furthermore, it is important to store the G2 pill out of reach of children and pets to prevent accidental ingestion.

Disposal Recommendations

Disposing of unused or expired medications like the G2 pill requires careful consideration to avoid environmental contamination and potential harm to others. Flushing medications down the toilet or throwing them in the trash can lead to pollution of water sources and pose risks to wildlife. Instead, individuals should look for local take-back programs offered by pharmacies or community centers. These programs provide a safe way to dispose of medications.


If take-back options are not available, there are safe disposal methods one can follow at home. For instance, mixing the pills with an unappealing substance—such as dirt, cat litter, or used coffee grounds—can deter accidental ingestion by children or animals. This mixture should then be placed in a sealed plastic bag before being thrown away in the household trash. Additionally, it is important to scratch out any personal information on prescription labels before disposing of empty containers to protect personal privacy.

Overdose Risks and What to Do

Overdoses can occur when an individual consumes a substance in quantities that exceed their body’s capacity to process it, leading to potentially life-threatening symptoms. Recognizing the signs of an overdose is crucial for timely intervention and can significantly impact the outcome. Common symptoms of overdose include severe nausea, stomach pain, dizziness, and difficulty breathing. These symptoms indicate that the body is struggling to cope with the excess substance, and immediate action is required.


The importance of adhering to prescribed dosage limits cannot be overstated. Many people underestimate the risks associated with taking medications, particularly opioids, which can dramatically affect respiratory function. When someone overdoses on opioids, their breathing may slow or even stop altogether, resulting in unconsciousness or death if not treated promptly. It is essential to follow medical advice and use medications only as directed to minimize the risk of overdose.


If you suspect that someone has overdosed, it is imperative to seek immediate medical attention. Calling emergency services should be your first step. While waiting for help to arrive, you can take measures to assist the affected individual. If naloxone is available—a medication that can temporarily reverse opioid overdoses—administering it can be life-saving. However, it is crucial to remember that naloxone’s effects may wear off before the person has fully recovered, necessitating further medical intervention.


In summary, understanding the risks associated with drug use and recognizing the signs of an overdose are vital skills that can save lives. Always adhere to prescribed dosages and seek help immediately if an overdose is suspected. The consequences of delay can be dire, making awareness and prompt action essential components in managing overdose situations effectively.

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FAQs About Ibuprofen and Its Effects


What are the most common side effects of taking ibuprofen regularly?

Regular use of ibuprofen can result in various side effects, primarily affecting the gastrointestinal system. Common symptoms include stomach pain, nausea, diarrhea, constipation, heartburn, and gas, often due to irritation of the stomach lining caused by NSAIDs like ibuprofen. Other frequently reported issues are dizziness, headaches, fatigue, and fluid retention, which may cause swelling in the ankles or feet.


For long-term or excessive use, the risks increase significantly, including gastrointestinal bleeding, ulcers, kidney damage, liver damage, and elevated blood pressure. In severe cases, individuals may experience internal bleeding (manifesting as black or bloody stools), yellowing of the skin or eyes (a sign of liver damage), or allergic reactions such as swelling, rash, or difficulty breathing. To minimize these risks, ibuprofen should be used only as directed and under the supervision of a healthcare provider for long-term treatment.

How does ibuprofen compare to other NSAIDs in terms of effectiveness?

Ibuprofen is one of the most widely used NSAIDs due to its balance of effectiveness and tolerability. It is particularly effective for general pain relief, inflammation reduction, and fever management. Studies show that ibuprofen performs comparably to other NSAIDs for acute pain and inflammation, with a relatively quick onset of action (30–60 minutes) making it ideal for short-term use.


While other NSAIDs like naproxen are longer-acting and better suited for chronic conditions such as arthritis, ibuprofen is often preferred for conditions requiring rapid symptom relief. Additionally, ibuprofen is less likely to cause gastrointestinal side effects at lower doses compared to some other NSAIDs. However, individual responses can vary, so consulting with a healthcare provider is essential to determine the most appropriate medication for your specific condition.

Are there any long-term risks associated with using ibuprofen?

Yes, long-term use of ibuprofen, particularly at high doses, is associated with several serious risks. Cardiovascular risks include an increased likelihood of heart attack, stroke, and heart failure, especially in individuals with pre-existing heart conditions. Gastrointestinal issues such as ulcers, bleeding, and stomach lining damage are also common in chronic use.


Additionally, prolonged ibuprofen use can impair kidney function, potentially leading to chronic kidney disease or acute renal failure. Liver damage and elevated blood pressure are further risks, along with less common side effects like cognitive impairment or tinnitus (ringing in the ears). These risks are higher in older adults and individuals with existing health conditions. It is critical to consult a healthcare provider for long-term pain management strategies to minimize these risks.

Can ibuprofen be taken with other medications without causing adverse interactions?

Ibuprofen interacts with several medications, and caution is necessary to avoid adverse effects. Combining ibuprofen with other NSAIDs, aspirin, or blood thinners increases the risk of gastrointestinal bleeding and ulcers. Similarly, ibuprofen may reduce the effectiveness of blood pressure medications (like ACE inhibitors and beta-blockers) and heighten the risk of kidney damage.


Antidepressants (e.g., SSRIs) and lithium can also interact with ibuprofen, potentially leading to increased side effects or toxicity. If you are taking any medication, over-the-counter drugs, or herbal supplements, consult a healthcare provider before adding ibuprofen to your regimen to ensure safety.

What should I do if I miss a dose of ibuprofen?

If you are taking ibuprofen on a regular schedule and miss a dose, take it as soon as you remember, provided it is not close to the time for your next dose. If it is nearly time for the next dose, skip the missed one and continue with your regular schedule. Do not double up doses to compensate for a missed dose, as this can increase the risk of side effects like stomach irritation or bleeding. If you are unsure, consult your healthcare provider or pharmacist for guidance.

What are the common uses for ibuprofen?

Ibuprofen is a versatile medication used for managing a variety of conditions:

  1. Pain Relief: Effective for headaches, muscle aches, toothaches, menstrual cramps, arthritis, and minor injuries.
  2. Fever Reduction: Lowers body temperature during illnesses like the flu or infections.
  3. Inflammation Management: Treats swelling and stiffness associated with conditions such as arthritis, tendonitis, and bursitis.
  4. Post-Surgery or Dental Pain: Alleviates discomfort after medical procedures.

This over-the-counter medication is available in various forms, including tablets, capsules, and liquid suspensions, making it accessible for different age groups and needs.

How does ibuprofen interact with blood thinners?

Combining ibuprofen with blood thinners like warfarin significantly increases the risk of bleeding. This is because both medications affect blood clotting mechanisms: ibuprofen inhibits platelet aggregation, while blood thinners slow down the clotting process. Together, these effects can lead to internal bleeding, particularly in the gastrointestinal tract. Individuals on blood thinners should avoid using ibuprofen unless specifically recommended by a healthcare provider.

How does kidney health influence the duration of ibuprofen in the system?

Kidney health plays a critical role in how ibuprofen is metabolized and excreted. In individuals with healthy kidney function, ibuprofen has a half-life of 2–4 hours, meaning it is cleared relatively quickly. However, in those with chronic kidney disease or impaired renal function, the drug’s clearance is slower, leading to prolonged retention in the body and an increased risk of toxicity. Regular monitoring and dosage adjustments are essential for individuals with kidney issues who require ibuprofen.

What are the best practices for storing ibuprofen pills?

To maintain ibuprofen’s potency and safety, store it in a cool, dry place at room temperature (68°F to 77°F or 20°C to 25°C). Avoid exposure to moisture, heat, and direct sunlight, which can degrade the medication. Bathrooms and kitchens are unsuitable storage locations due to humidity fluctuations. Keep ibuprofen in its original container with a tightly closed lid and store it out of reach of children and pets to prevent accidental ingestion.

How effective is the orange pill G2 for treating menstrual cramps?

The orange pill G2, containing 200 mg of ibuprofen, is highly effective for relieving menstrual cramps (dysmenorrhea). It works by reducing the production of prostaglandins, hormone-like substances that cause uterine contractions and pain during menstruation. For best results, it is recommended to take ibuprofen at the first sign of cramps, as this helps reduce the severity of symptoms. Ibuprofen’s fast-acting nature makes it a preferred choice for managing period pain.

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