Wellbutrin withdrawal is a challenging experience that many individuals face when discontinuing this commonly prescribed antidepressant. As a medication primarily used to treat depression and aid in smoking cessation, Wellbutrin (generic name: bupropion) can lead to withdrawal symptoms when stopped abruptly or even when tapered off gradually.
Understanding the nature of Wellbutrin withdrawal, its symptoms, and how to manage them is crucial for anyone considering stopping their medication or experiencing discontinuation effects.
Wellbutrin withdrawal occurs when a person who has been taking the medication for an extended period stops or reduces their dosage. This phenomenon is part of what’s known as antidepressant discontinuation syndrome. Unlike selective serotonin reuptake inhibitors (SSRIs) like Zoloft, Prozac, and Lexapro, Wellbutrin primarily affects dopamine and norepinephrine levels in the brain, leading to a unique set of withdrawal symptoms.
It’s important to note that experiencing withdrawal from Wellbutrin doesn’t indicate addiction. Rather, it’s a sign that the body has become accustomed to the medication and needs time to readjust. Withdrawal can occur even when the medication is tapered off under medical supervision, although symptoms are typically less severe than SSRI withdrawal.
Wellbutrin withdrawal symptoms can include headaches, nausea, anxiety, and mood swings. To minimize these effects, it’s recommended to taper off the medication gradually under a doctor’s guidance, typically over several weeks or months.
The symptoms of Wellbutrin withdrawal can vary from person to person, but they generally fall into three main categories: physical, psychological, and neurological.
✅ Headaches
✅ Nausea
✅ Dizziness
✅ Fatigue
✅ Tremors
✅ Body aches
✅ Anxiety
✅ Depression
✅ Mood swings
✅ Irritability
✅ Suicidal thoughts (seek immediate help if present)
✅ Brain fog
✅ Difficulty concentrating
✅ Numbness or tingling sensations
✅ Brain zaps (sudden electric shock-like sensations in the head)
Yes, Wellbutrin withdrawal occurs when the brain adjusts to the absence of the medication. While it is typically milder than SSRI withdrawal, it can still cause discomfort, especially when stopped suddenly.
The timeline for Wellbutrin withdrawal depends on factors such as dosage, duration of use, and individual physiology. However, a general timeline can be outlined based on the medication’s half-life, which is approximately 21 hours with regular use.
Time After Stopping Wellbutrin Expected Withdrawal Symptoms 0-48 hours. Early symptoms begin as Wellbutrin levels drop (mild headaches, nausea, mood shifts). Days 3-7 Peak withdrawal symptoms—brain zaps, irritability, nausea, and sleep disturbances. Weeks 2-4. Symptoms begin to decrease in intensity, but some may experience lingering anxiety or fatigue. Beyond 1 month. Most symptoms resolve, though mood instability or cravings may persist in some cases.
📌 Factors That Affect Withdrawal Duration:
The most effective way to prevent or minimize withdrawal symptoms is through a gradual tapering process.
📉 Week 1: Reduce dose by 25%
📉 Week 2: Reduce dose by another 25%
📉 Week 3: Reduce by 50%
📉 Week 4: Discontinue (or continue tapering based on symptoms)
📌 Important: Always consult a doctor before tapering. Some people may need a slower taper, while others may tolerate a faster schedule.
💡 Switching Medications? Some healthcare providers may recommend transitioning to another antidepressant if Wellbutrin is being discontinued due to side effects.
While tapering off Wellbutrin, certain lifestyle adjustments can help manage withdrawal symptoms:
✅ Stay hydrated and eat balanced, nutrient-dense meals.
✅ Use over-the-counter pain relievers for headaches or body aches.
✅ Get adequate sleep and avoid caffeine before bedtime.
✅ Practice mindfulness, meditation, and deep breathing exercises.
✅ Seek therapy or join a support group to talk about symptoms.
✅ Engage in low-impact exercise like yoga or walking.
🚫 What to Avoid:
❌ Alcohol and stimulants (can worsen symptoms).
❌ Sudden lifestyle changes that add stress to the body.
If you or a loved one are experiencing Wellbutrin withdrawal symptoms or dependence, you don’t have to go through it alone. Asana Recovery offers professional treatment options tailored to your needs, ensuring a safe and supported detox process.
🩺 Medical Detox – 24/7 supervision to help manage withdrawal symptoms safely.
🏠 Outpatient Treatment – Structured support while continuing daily responsibilities.
🧠 Inpatient Rehab – Comprehensive care for individuals with co-occurring mental health challenges.
💡 Personalized recovery plans help ease the transition, ensuring you receive the care you deserve.
📞 Call us today to speak with a specialist about detox and recovery options.
🔗 Learn More About Our Treatment Programs
No, stopping Wellbutrin suddenly increases the risk of severe withdrawal symptoms. A tapering plan is recommended.
Withdrawal can last from a few days to several weeks, depending on the dose and tapering speed.
Yes, brain zaps—electric shock-like sensations—are a common symptom, though less frequent than with SSRIs.
Gradual dose reduction, hydration, healthy nutrition, exercise, and therapy can help manage symptoms.
No, some people experience mild to no withdrawal, while others have more intense symptoms.
This book has helped so many men and women; and we want to give it you for FREE. Get signed up today and discover how to unlock the grip of addiction and get back to living your best life.
In this book, you’ll discover…
— The Most Common Misconceptions About Addiction and Rehab
— Why Rock Bottom is a Myth and What You Can Do About It
–The Steps to Healing From Trauma, Both Mentally and Emotionally
–And much more!
Asana Recovery is licensed and certified by the State Department of Health Care Services.
© Copyright 2024 Asana Recovery™ | All Rights Reserved | Privacy Policy
You could save up to 100% of your treatment using your Insurance.
Asana Recovery
We firmly believe that the internet should be available and accessible to anyone, and are committed to providing a website that is accessible to the widest possible audience, regardless of circumstance and ability.
To fulfill this, we aim to adhere as strictly as possible to the World Wide Web Consortium’s (W3C) Web Content Accessibility Guidelines 2.1 (WCAG 2.1) at the AA level. These guidelines explain how to make web content accessible to people with a wide array of disabilities. Complying with those guidelines helps us ensure that the website is accessible to all people: blind people, people with motor impairments, visual impairment, cognitive disabilities, and more.
This website utilizes various technologies that are meant to make it as accessible as possible at all times. We utilize an accessibility interface that allows persons with specific disabilities to adjust the website’s UI (user interface) and design it to their personal needs.
Additionally, the website utilizes an AI-based application that runs in the background and optimizes its accessibility level constantly. This application remediates the website’s HTML, adapts Its functionality and behavior for screen-readers used by the blind users, and for keyboard functions used by individuals with motor impairments.
If you’ve found a malfunction or have ideas for improvement, we’ll be happy to hear from you. You can reach out to the website’s operators by using the following email
Our website implements the ARIA attributes (Accessible Rich Internet Applications) technique, alongside various different behavioral changes, to ensure blind users visiting with screen-readers are able to read, comprehend, and enjoy the website’s functions. As soon as a user with a screen-reader enters your site, they immediately receive a prompt to enter the Screen-Reader Profile so they can browse and operate your site effectively. Here’s how our website covers some of the most important screen-reader requirements, alongside console screenshots of code examples:
Screen-reader optimization: we run a background process that learns the website’s components from top to bottom, to ensure ongoing compliance even when updating the website. In this process, we provide screen-readers with meaningful data using the ARIA set of attributes. For example, we provide accurate form labels; descriptions for actionable icons (social media icons, search icons, cart icons, etc.); validation guidance for form inputs; element roles such as buttons, menus, modal dialogues (popups), and others. Additionally, the background process scans all the website’s images and provides an accurate and meaningful image-object-recognition-based description as an ALT (alternate text) tag for images that are not described. It will also extract texts that are embedded within the image, using an OCR (optical character recognition) technology. To turn on screen-reader adjustments at any time, users need only to press the Alt+1 keyboard combination. Screen-reader users also get automatic announcements to turn the Screen-reader mode on as soon as they enter the website.
These adjustments are compatible with all popular screen readers, including JAWS and NVDA.
Keyboard navigation optimization: The background process also adjusts the website’s HTML, and adds various behaviors using JavaScript code to make the website operable by the keyboard. This includes the ability to navigate the website using the Tab and Shift+Tab keys, operate dropdowns with the arrow keys, close them with Esc, trigger buttons and links using the Enter key, navigate between radio and checkbox elements using the arrow keys, and fill them in with the Spacebar or Enter key.Additionally, keyboard users will find quick-navigation and content-skip menus, available at any time by clicking Alt+1, or as the first elements of the site while navigating with the keyboard. The background process also handles triggered popups by moving the keyboard focus towards them as soon as they appear, and not allow the focus drift outside it.
Users can also use shortcuts such as “M” (menus), “H” (headings), “F” (forms), “B” (buttons), and “G” (graphics) to jump to specific elements.
We aim to support the widest array of browsers and assistive technologies as possible, so our users can choose the best fitting tools for them, with as few limitations as possible. Therefore, we have worked very hard to be able to support all major systems that comprise over 95% of the user market share including Google Chrome, Mozilla Firefox, Apple Safari, Opera and Microsoft Edge, JAWS and NVDA (screen readers).
Despite our very best efforts to allow anybody to adjust the website to their needs. There may still be pages or sections that are not fully accessible, are in the process of becoming accessible, or are lacking an adequate technological solution to make them accessible. Still, we are continually improving our accessibility, adding, updating and improving its options and features, and developing and adopting new technologies. All this is meant to reach the optimal level of accessibility, following technological advancements. For any assistance, please reach out to