Call Us

(949) 763-3440

Text Us

(949) 763-3440

Covered?

Verify Now

Contact

Send Us a Message

Delirium Tremens (DTs)

Delirium Tremens (DTs)

Table of Contents

Delirium Tremens (DTs) represents the most severe and life-threatening form of alcohol withdrawal. This condition typically emerges 48-72 hours after a person with alcohol use disorder suddenly ceases heavy drinking. DTs are associated with life-threatening neurological and cardiovascular symptoms, including hallucinations, tremors, seizures, and autonomic instability. Delirium tremens occurs in approximately 3-5% of individuals with chronic alcohol dependence, and untreated cases have a mortality rate ranging from 15-37%.


The term “delirium tremens” is derived from Latin, where “delirium” refers to confusion and “tremens” refers to trembling, which are hallmark symptoms of this condition. Although the onset typically occurs within 2-3 days after alcohol cessation, delirium tremens symptoms can appear as late as 10 days in some cases, especially in patients with concurrent medical conditions like metabolic disorders or liver disease.

Understanding the Causes of Delirium Tremens (DTs)

The pathophysiology of DTs involves complex neurochemical imbalances that significantly affect the brain and nervous system.

  • GABA Suppression: Chronic alcohol use increases the brain’s reliance on the GABA system, the body’s primary inhibitory neurotransmitter. When alcohol use is abruptly stopped, the resulting GABA deficit leads to neuronal hyperactivity.
  • Glutamate Surge: Alcohol also inhibits NMDA glutamate receptors, and with withdrawal, there is an overactivation of glutamate, which contributes to the intense symptoms of delirium tremens such as seizures and autonomic instability.
  • Neuroendocrine Dysregulation: Alcohol withdrawal triggers an increase in stress hormones such as cortisol and catecholamines, which can worsen symptoms like tachycardia and high blood pressure.

Key Risk Amplifiers:

  • Prior DTs episodes (60% recurrence risk)
  • Hypomagnesemia and hypokalemia
  • Concurrent use of other substances like benzodiazepines
  • Hepatic encephalopathy

    What Are the Symptoms of Delirium Tremens (DTs)?

    Delirium Tremens manifests through a triad of autonomic hyperactivity, neuropsychiatric disturbances, and metabolic derangements. These symptoms can be both physical and psychological.

    Physical Symptoms:

  • Tachycardia (>120 bpm)
  • Hyperthermia (100.4-104°F)
  • Diaphoresis (excessive sweating)
  • Myoclonic jerks (muscle spasms)
  • Orthostatic hypotension (low blood pressure when standing)
  • Severe tremors and shaking hands
  • Seizures (in severe cases)

Psychological Symptoms:

  • Visual and auditory hallucinations (in 80% of cases)
  • Paranoia and illogical speech
  • Tactile hallucinations (feeling sensations like “crawling skin”)
  • Disorientation and confusion
  • Fluctuating consciousness (delirium)

Critical Complications:

  • Rhabdomyolysis due to prolonged tremors
  • Aspiration pneumonia from swallowing difficulties
  • QT prolongation, which can lead to torsades de pointes

Addiction Treatment Covered by Insurance

Asana Recovery works with most PPO plans, covering up to 100%. See if your insurance can help fund your journey. Click below to get a free quote. 

When Do Delirium Tremens (DTs) Symptoms Start?

The timeline of DTs development follows a typical pattern:

  1. 6-24 hours: Early symptoms like mild anxiety, tremors, nausea, and general restlessness.
  2. 24-48 hours: Onset of alcoholic hallucinosis, which includes auditory and visual hallucinations without delirium.
  3. 48-72 hours: Full-blown DTs presentation, marked by autonomic storm, delirium, fever, severe tremors, and seizures.
  4. Day 5 and beyond: Symptoms begin to subside with proper medical intervention.

In some cases, especially with polysubstance abuse, the onset can be delayed up to 7-10 days after the last drink.

Diagnosis of Delirium Tremens (DTs)

Diagnosing DTs involves both clinical evaluation and specific diagnostic tests:

1. CIWA-Ar Scale:

  • A 10-item scale that assesses the severity of alcohol withdrawal symptoms. A score of ≥20 indicates a high risk of developing delirium tremens.

2. Metabolic Panel:

  • Tests for hypomagnesemia and hypokalemia, common in alcohol withdrawal.
  • Monitoring for respiratory alkalosis and electrolyte imbalances.

3. Neuroimaging:

  • MRI to exclude conditions like hemorrhagic stroke or other causes of neurological deficits that mimic DTs.

4. EEG:

  • Helps differentiate DTs from non-convulsive status epilepticus.


    Differential diagnoses include conditions like serotonin syndrome and anticholinergic toxicity, which must be ruled out to confirm delirium tremens.

    Treatment for Delirium Tremens (DTs)

    Management of DTs is vital for survival. Treatment focuses on symptom control and stabilizing the patient’s condition:

    1. Benzodiazepines:

  • First-line treatment: Lorazepam (2-4mg IV) given every 10-15 minutes to manage symptoms.
  • Refractory cases: Midazolam infusion (0.1-0.3mg/kg/hr) for patients who don’t respond to benzodiazepines.

2. Adjunctive Therapies:

  • Propofol for intubated patients to control symptoms.
  • Dexmedetomidine for sympathetic overdrive.
  • Thiamine (500mg IV TID) to prevent Wernicke’s encephalopathy.

3. Environmental Control:

  • Low-stimulation settings, such as ICU rooms with 1:1 nursing care, to help reduce agitation.

4. Fluid Management:

  • Balanced crystalloids (e.g., Plasma-Lyte) to correct dehydration and electrolyte imbalances.

    Complications of Delirium Tremens (DTs)

    Acute complications from DTs include:

  • Malignant arrhythmias from electrolyte imbalances.
  • Acute kidney injury due to prerenal azotemia.
  • Aspiration pneumonitis from impaired swallowing.

Chronic complications can persist even after initial stabilization:

  • Korsakoff psychosis (memory loss) and cerebellar degeneration (coordination issues).
  • Central pontine myelinolysis from rapid correction of sodium levels.

    Prevention of Delirium Tremens (DTs)

    Prevention is key for high-risk individuals. Strategies include:

    1. CIWA-guided Tapering:

  • Gradual benzodiazepine tapering over 5-7 days, supervised by a healthcare provider.

    2. Vitamin Replenishment:

  • Thiamine (100mg daily) and folate (1mg) to prevent deficiencies and complications.

    3. Transitional Care:

  • Medications like naltrexone or acamprosate after detox to maintain sobriety.

Conclusion: Key Takeaways

Delirium Tremens (DTs) is a neurological emergency requiring ICU-level care. Early recognition and benzodiazepine administration can reduce mortality from 35% to under 5%. Once stabilized, patients should undergo comprehensive addiction treatment, including cognitive behavioral therapy (CBT) and medication-assisted treatment (MAT), to prevent relapse.
Incorporated Keywords: Dts symptoms, what is dts alcohol, delirium tremens symptoms timeline, can alcohol withdrawal cause seizures, delirium tremens treatment.

Seeking Help for Delirium Tremens at Asana Recovery

If you or a loved one is experiencing alcohol withdrawal symptoms, including Delirium Tremens (DTs), it’s crucial to seek professional help immediately. At Asana Recovery, we offer specialized detox and addiction treatment programs to safely manage alcohol withdrawal and reduce the risk of serious complications. Don’t face this journey alone—reach out to Asana Recovery today and take the first step toward a healthier, sober future.

Find Your First Step in Recovery, Supported by Shared Experience

We get it. Addiction recovery is tough. That’s why our programs are founded and staffed by people in recovery – people who truly understand.

Frequently Asked Questions about Delirium Tremens (DTs)


1. What is Delirium Tremens (DTs)?

Delirium Tremens (DTs) is a severe form of alcohol withdrawal that occurs in individuals with alcohol use disorder. It typically begins 48-72 hours after the last drink, though symptoms can start up to 10 days later in some cases. It presents with tremors, hallucinations, seizures, and autonomic instability, and if left untreated, it can lead to life-threatening complications.

2. What are the symptoms of Delirium Tremens (DTs)?

The symptoms of DTs include physical manifestations like tremors, high blood pressure, fever, and sweating. Psychological symptoms such as visual and tactile hallucinations, confusion, and severe agitation are common. In severe cases, DTs can also cause seizures and heart failure.

3. When do Delirium Tremens (DTs) symptoms start?

Typically, Delirium Tremens symptoms begin within 48-72 hours after stopping alcohol consumption, but they can start anywhere from 6 hours to 10 days later, especially if the person has a history of alcohol withdrawal or polysubstance abuse.

4. How long do Delirium Tremens (DTs) last?

DTs usually last between 2-3 days, but the most severe symptoms can continue up to a week in some cases. With proper treatment, the duration and severity of symptoms can be minimized.

5. What is the treatment for Delirium Tremens (DTs)?

Treatment for DTs typically involves benzodiazepines like lorazepam to control agitation and prevent seizures. Other supportive treatments may include intravenous fluids, thiamine supplementation to prevent Wernicke’s encephalopathy, and medications to manage blood pressure and heart rate.

6. Can Delirium Tremens (DTs) kill you?

Yes, Delirium Tremens is a life-threatening condition if not treated immediately. Untreated DTs can lead to complications like heart attack, stroke, seizures, and respiratory failure, all of which can be fatal.

7. What causes Delirium Tremens (DTs)?

DTs occur as a result of abrupt alcohol withdrawal in individuals who have been heavy drinkers for a long time. Alcohol is a depressant, and when someone with a history of chronic alcohol use stops drinking suddenly, the brain becomes overstimulated due to changes in neurotransmitter levels like glutamate and GABA.

8. What are the risk factors for developing Delirium Tremens (DTs)?

Risk factors for DTs include previous episodes of DTs, long-term heavy drinking (especially more than 10 years), a history of seizures, and certain medical conditions like liver disease. Additionally, people who misuse other substances like benzodiazepines may also be at higher risk.

9. How can I prevent Delirium Tremens (DTs)?

The best way to prevent DTs is to slowly taper off alcohol under medical supervision, rather than quitting abruptly. This can be done with the help of a healthcare provider, who may recommend medications like benzodiazepines to ease withdrawal symptoms.

10. What is the difference between alcohol withdrawal and Delirium Tremens (DTs)?

Alcohol withdrawal refers to the range of symptoms that occur when a person reduces or stops alcohol consumption after prolonged use. Delirium Tremens (DTs) is the most severe form of alcohol withdrawal and is characterized by dangerous symptoms such as severe confusion, hallucinations, and seizures.

11. Can alcohol withdrawal cause seizures or a heart attack?

Yes, alcohol withdrawal, particularly in individuals with a history of chronic alcohol use, can lead to seizures and even heart attacks due to the strain on the cardiovascular system caused by autonomic instability and electrolyte imbalances during withdrawal.

12. How is Delirium Tremens (DTs) diagnosed?

DTs is typically diagnosed through a combination of clinical assessment and diagnostic tests, including the CIWA-Ar scale to assess withdrawal severity, blood tests to check electrolyte levels, and neuroimaging (like an MRI) to rule out other conditions such as a stroke.

13. How do I know if I am experiencing Delirium Tremens (DTs)?

If you have a history of heavy alcohol use and are experiencing severe withdrawal symptoms such as shaking (tremors), hallucinations, confusion, and seizures, you may be experiencing DTs. Seek medical attention immediately as DTs can become life-threatening without prompt treatment.

14. How can I stop alcohol withdrawal shakes?

Managing alcohol withdrawal shakes requires medical supervision. Treatment may include medications like benzodiazepines to control anxiety and tremors, as well as intravenous fluids and electrolyte replenishment to address dehydration and imbalances caused by alcohol withdrawal.

15. How do I get help for alcohol withdrawal and Delirium Tremens (DTs)?

If you or someone you know is experiencing symptoms of alcohol withdrawal or Delirium Tremens (DTs), seek immediate medical help. At Asana Recovery, we specialize in providing comprehensive detox and treatment programs to safely manage alcohol withdrawal and help individuals recover from alcohol use disorder. Call us today to learn more about how we can support you or your loved one through this challenging process.

Informational Sources

  1. MedlinePlus. (n.d.). Delirium tremens. U.S. National Library of Medicine. Retrieved from https://medlineplus.gov/ency/article/000766.htm
  2. National Institutes of Health. (2019). Delirium tremens. In StatPearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK482134
  3. WebMD. (2024). Delirium tremens: What you need to know. Retrieved from https://www.webmd.com/mental-health/addiction/delirium-tremens
  4. PubMed Central. (2019). Alcohol withdrawal delirium: Current trends and approaches to management. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC6286444/

Take the first step

Take your first step towards lasting recovery. At Asana, we offer effective, insurance-covered treatment for addiction and mental health, guided by experts who understand because they’ve been there. Start your healing today.

Meet the Book That’s
Changing Lives

Asana Recovery - Premier Addiction Treatment Center In Orange County-Recovery Starts Here - Aasana Recovery - Original_Page_01 1(1)

Meet the Book That’s
Changing Lives

This book has helped so many men and women; and we want to give it you for FREE. Get signed up today and discover how to unlock the grip of addiction and get back to living your best life.

In this book, you’ll discover…

— The Most Common Misconceptions About Addiction and Rehab

 

— Why Rock Bottom is a Myth and What You Can Do About It

 

–The Steps to Healing From Trauma, Both Mentally and Emotionally

 

–And much more!

Verify Insurance for Free

You could save up to 100% of your treatment using your Insurance.

We are in-network with Cigna Insurance.
We are in-network with BlueCross BlueShield Insurance.
We are in-network with Magellan Health Insurance.
We are in-network with Aetna Insurance.
We are in-network with Anthem Insurance.
We are in-network with Beacon Health Options Insurance.

We're Here to Help

Take the first step toward a better future—call us today!