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Hydroxyzine and Alcohol: A Dangerous Combination You Should Avoid

Hydroxyzine and Alcohol: A Dangerous Combination You Should Avoid

Table of Contents

Hydroxyzine is a widely prescribed antihistamine medication used to treat anxiety, allergies, and itching. While generally safe when taken as prescribed, combining hydroxyzine with alcohol can lead to serious health risks. Let’s explore why this combination should be avoided and what you need to know to stay safe.

Understanding Hydroxyzine

Hydroxyzine works by blocking histamine, a natural substance your body produces during allergic reactions. It also has sedating properties that make it effective for treating anxiety. The medication typically starts working within 15-30 minutes and its effects can last for 4-6 hours.

Common Uses:

  • Anxiety treatment
  • Allergy symptom relief
  • Pre-surgery sedation
  • Itching relief

Why Alcohol and Hydroxyzine Don’t Mix

The combination of hydroxyzine and alcohol creates a dangerous amplification effect on your central nervous system. Both substances are CNS depressants, meaning they slow down brain activity and vital functions like breathing and heart rate.

Primary Risks:

  • Excessive sedation
  • Impaired coordination
  • Decreased cognitive function
  • Potential respiratory depression

Dangerous Side Effects

When hydroxyzine and alcohol interact, they can cause several concerning symptoms:

Short-term Effects:

  • Extreme drowsiness
  • Dizziness
  • Difficulty concentrating
  • Dry mouth
  • Blurred vision
  • Impaired judgment

Severe Complications:

  • Heart rhythm problems
  • Breathing difficulties
  • Risk of falls and accidents
  • Potential unconsciousness

High-Risk Groups

Certain individuals face greater dangers when mixing hydroxyzine and alcohol:

Increased Risk Factors:

  • Adults over 65
  • People with liver or kidney problems
  • Those with heart conditions
  • Individuals taking other CNS depressants

Safety Guidelines

To use hydroxyzine safely, follow these essential precautions:

Best Practices:

  • Never combine hydroxyzine with alcohol
  • Take medication exactly as prescribed
  • Wait at least 24 hours after taking hydroxyzine before consuming alcohol
  • Inform your healthcare provider about any alcohol use

When to Seek Emergency Care

Seek immediate medical attention if you experience these symptoms after mixing hydroxyzine and alcohol:

Warning Signs:

  • Severe dizziness or fainting
  • Irregular heartbeat
  • Difficulty breathing
  • Extreme confusion
  • Uncontrollable tremors

Alternative Options

If you’re prescribed hydroxyzine but want to consume alcohol occasionally, discuss these alternatives with your healthcare provider:

Possible Solutions:

  • Non-sedating antihistamines for allergies
  • Different anxiety medications
  • Alternative anxiety management techniques

Professional Guidance

The safest approach is complete avoidance of alcohol while taking hydroxyzine. If you struggle with alcohol use or anxiety, speak with your healthcare provider about developing an appropriate treatment plan that addresses both concerns.


Remember, your safety is paramount. Never adjust your medication dosage or combine substances without first consulting your healthcare provider. The risks of mixing hydroxyzine and alcohol far outweigh any potential short-term benefits.


At Asana Recovery, we understand the challenges of managing anxiety or other conditions while addressing alcohol use. Combining substances like hydroxyzine and alcohol can lead to dangerous side effects, but our team is here to help you navigate these challenges safely. Whether you’re struggling with substance use, medication management, or both, Asana Recovery offers personalized treatment plans tailored to your unique needs. Contact us today to learn how we can support your journey to better health and lasting recovery.

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